The Impact of Verapamil on Catecholamine Polymorphic Ventricular Tachycardia
نویسنده
چکیده
Catecholaminergic polymorphic ventricular tachycardia (CPVT) is a disease of mutation of family genes associated with exercise-induced syncope or sudden death. We report a case of a 27-year-old female with CPVT who had experienced several episodes of syncope and had been prescribed beta-blocker regularly. Sudden onset of ventricular arrhythmia occurred and the patient was resuscitated but remained in comatose state. During her hospitalization, the refractory intermittent ventricular arrhythmia was finally terminated adjuvantly by use of verapamil, while the current standard therapy for CPVT was definitely not useful. Therefore, we report this case accompanied by a review of the current literature.
منابع مشابه
Polymorphic ventricular tachyarrhythmias in the absence of organic heart disease: classification, differential diagnosis, and implications for therapy.
Different polymorphic ventricular tachyarrhythmias may cause syncope or cardiac arrest in patients with no heart disease: (1) Catecholamine-sensitive polymorphic ventricular tachycardia (VT) presents during childhood: the hallmark is the reproducible provocation of atrial and polymorphic ventricular arrhythmias during exercise, despite a normal QT. Beta-blockers are the treatment of choice. (2)...
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